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Non-clinical test systems there is a need to develop more relevant human-derived in vitro systems to improve the assessment of cMRTPs and gradually replace in vivo rodent models

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moreover, the study shows that whereas the startup costs of rechargeable NVPs are relatively high, once the purchasing is done, extra costs of refilling the cartridges, charging dead and replacing dead batteries, replacing worn-out coils, and overall maintenance of the device are way more attractive than comparable units of combustible cigarettes