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The FDA uses the term "fatal flaw" to submit PMTAs without specific research, and it has been at the center of almost all lawsuits against the agency's PMTA process

Some of the common lung cancer symptoms are as follows: Severe cough that worsens over time and fails to go away Blood in sputum Severe chest pain Hoarseness (change in the voice, which sounds breathy and rough) Difficulty in breathing Unexplained weight loss Constant feeling of tiredness and weakness Body and joint pain accompanied by a headache What are the treatment options for lung cancer