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A filter, either purchased or made from cardboard, may be attached to one end

Nearly 9 out of 10 adults who smoke cigarettes daily first tried smoking by the age of 18 (CDC, 2024) Among past-month users of nicotine products, nearly two thirds of adolescents aged 12 to 17 (63.1%) vaped nicotine but did not use tobacco products (SAMHSA, 2022)

and Europe using a single DNA methylation platform

Ecotoxicol Environ Saf 182:109418 Hoffman SJ, Mammone J, Van Katwyk SR, Sritharan L, Tran M, Al-Khateeb S, Grjibovski A, Gunn E, Kamali-Anaraki S, Li B (2019) Cigarette consumption estimates for 71 countries from 1970 to 2015: systematic collection of comparable data to facilitate quasi-experimental evaluations of national and global tobacco control interventions