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Some Things Get Better with Time, but Not Tobacco Smoke Residue Thirdhand Smoke Resource Center Cigarette smoke is made up of thousands of chemicals, and among them is hydrogen cyanide a highly toxic substance also found in certain poisons. It's created when tobacco burns and is Chemicals found in hookah smoke versus cigarette smoke. (Adapted from Download Table Content of toxic components of cigarette, cigarette smoke vs cigarette butts: A comprehensive systematic review ScienceDirect
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