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In adjusted models that included only those who did not use conventional cigarettes at baseline and adjusted for gender, age, race/ethnicity, maternal educational level, sensation seeking, parental cigarette smoking, and peer cigarette smoking, baseline e-cigarette use was independently associated with progression to cigarette smoking (OR = 8.3, 95% CI, 1.258.6) and susceptibility to cigarette smoking (OR = 8.5, 95% CI, 1.357.2)

Analysis Analyses were primarily descriptive, including categories of tobacco product use, related attitudes, knowledge, exposure, and demographic characteristics

Still, the psychological effect is unmistakable: anyone who expected a defensive consumer staple to protect capital has had to watch the ticker grind lower while headline after headline questioned the durability of the legacy combustibles business