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61 The authors concluded that tobacco cessation is warranted in smokers with chronic obstructive pulmonary disease . 61 Smoking Damages Endothelial Cells The impact of smoking on cardiovascular disease remained controversial until the early 1960s, when the giant Framingham heart disease study showed smokings heart-related dangers

Six decades after the first documentations of the deleterious health effects of tobacco use 24 , there has been substantial progress in reducing the prevalence of tobacco smoking worldwide

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This happened after Walt Disney, the founder of the company died of lung cancer