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New Brunswick and London: Rutgers University Press, 1987, pp

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Th2/Tc2 cells can be differentiated under IL-4 conditions and produce IL-4, IL-5 and IL-13 through GATA-3 and GATA-3, STAT6, respectively ( Th17 cells are characterized by the release of proinflammatory cytokines, such as IL-17A, IL-17F, IL-21 and IL-22, which are associated with COPD progression and the exacerbation of alveolar destruction (56)