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Co-administration of an OCT2 inhibitor, cimetidine (300 mg four times daily), with varenicline (2 mg single dose) to 12 smokers increased the systemic exposure of varenicline by 29% (90% CI: 21.5%, 36.9%) due to a reduction in varenicline renal clearance

Consider establishing smoke-free zones at home or in social activities to reduce the temptation

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Among high school JUUL users, 67.5% reported that their preferred flavor was mint or menthol