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But occasionally I chew nicotine gum

Among these, flavonoids in tobacco leaves are synthesized through pathways such as flavone and flavonol biosynthesis, as well as the phenylpropanoid pathway, under the action of various enzymes, including flavonol synthase (FLS) and phenylalanine ammonia-lyase (PAL) [15]

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Smoking remains a leading cause of heart disease, stroke, chronic lung disease, and various cancersincluding those of the mouth, throat, esophagus, stomach, colon, pancreas, and liver