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"I've always wanted to be able to express myself in completely different characters, in the upper echelon of quality," Travolta says

By contrast, the diversion hypothesis proposes that e-cigarettes reduce smoking among high-risk users who would be liable to initiate smoking in the absence of e-cigarettes by providing an alternative to satisfy a propensity to explore novel experiences (Etter, 2017

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The structural differences among phytocannabinoids, endocannabinoids and synthetic cannabinoids result in unique pharmacological profiles, which influence their efficacy and toxicity in both therapeutic and recreational settings (Fig