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PMC 3399759

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Key Takeaways Most swollen lymph nodes are benign and result from common infections like colds, flu, or bacterial infections that resolve within 2-4 weeks Location matters : Localized swelling typically indicates regional infection, while generalized enlargement may suggest systemic conditions Seek medical care immediately if nodes are hard, fixed, rapidly growing, or accompanied by fever, night sweats, and unexplained weight loss Recent infections or vaccinations commonly cause temporary lymph node enlargement as part of normal immune response Size and texture provide clues : Soft, mobile, tender nodes usually indicate infection, while hard, fixed nodes may suggest more serious conditions Understanding Lymph Nodes and Their Function What Are Lymph Nodes