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The Swedish government requested assistance from a pharmaceutical company, and in 1967 Ove Ferno, a researcher at Pharmacia (now merged with Pfizer), developed a nicotine replacement gum to placate the symptoms of withdrawal

This pattern suggests that phytocannabinoids might selectively affect gonadal androgen synthesis without altering adrenal or peripheral pathways, possibly via direct effects on the testes, or disruption of the hypothalamicpituitarygonadal (HPG) axis function

Research comparing these groups found nearly identical death rates from cardiovascular disease, chronic obstructive pulmonary disease, and various cancers

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