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It is known, however, that certain factors influence the development of cancer

Shakespeares source for the tragedy is the account of Macbeth, King of Scotland, Macduff, and Duncan in Holinsheds Chronicles (1587), a history of England, Scotland, and Ireland familiar to Shakespeare and his contemporaries, although the events in the play differ extensively from the history of the real Macbeth

According to the Centers for Disease Control and Prevention, of adult smokers in the U.S., 28.9% live below the poverty level, while 18.3% of smokers live at or above the poverty level

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