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Wounds Nicotine reduces the nutritional blood flow to injured tissue and slows down the healing process

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But then another review of the public health benefits was ordered

Effect of Volatile Organic Compounds on Intestinal Microbiota Cigarette smoke contains large amounts of toxic volatile organic compounds (VOCs), such as isoprene, acrylonitrile, 1, 3-butadiene, acrylonitrile, styrene and benzene, which are inhaled into respiratory tract and induce different diseases, such as respiratory and cardiovascular diseases, and cancers (Pazo et al., 2016)