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doi: 10.1371/journal.pone.0027137 164

The American Cancer Society recommended the minimum age of 18 in 1963, the American Medical Association recommended 21 in 1985, [3] and the United States Department of Health and Human Services Office of the Inspector General recommended 19 or 21

Conclusion The recognition of the molecular mechanisms of the epigenetic changes in abnormal inflammation is expected to contribute to the understanding of the pathophysiology of CS-related diseases such that novel epigenetic therapies may be identified in the near future

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