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The most common nicotine withdrawal symptoms are: Irritability and anger Restlessness or difficulty concentrating Depression or anxiety Physical sensations, like you have a mild case of the flu Headaches and dizziness Inability to sleep uninterrupted Cravings for cigarettes Weight gain, though typically less than 10 pounds Nicotine Withdrawal and Strategies for Quitting Nicotine withdrawal can be unpleasant for most smokers, Dr