Other studies have identified known toxins present in the gaseous emissions
A meta-analysis published in 2015 in the British Medical Journal analysed the genetic information of nearly 1,50,000 current, former, and non-smokers and found that a gene variant associated with heavy smoking can lead to an increase in waist circumference
To gather relevant publications, we searched several databases such as PubMed, EBSCO, Cochrane, and Science Direct, using specific MESH terms and keywords such as cigarette smoking, air pollution, particulate matter, gaseous air pollutants, cardiovascular diseases, and hypertension. To ensure the quality of the studies, we applied PECOS criteria that focused on the population (i.e., adults chronically exposed to outdoor air pollutants), comparator (unexposed persons), result (all-cause mortality and cardiovascular diseases), and study design (experimental and epidemiological studies, intervention studies, meta-analyses, and systematic reviews published in peer-reviewed journals in English)
Exposure to second-hand smoke also poses significant health risks, as it can contribute to the same conditions that lead to strokes in cigarette smokers