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The database comprehensively covers more than 10000 common and important metabolites, including more than 2000 standard samples (including RT, MS1, MS2 dimensional identification information), mainly including amino acids and their derivatives, organic acids and their derivatives, carbohydrates and their derivatives, organic heterocycles, nucleosides and their derivatives, indoles and their derivatives, steroids and their derivatives, bile acids and their derivatives, acylcarnitine, hemolytic phospholipids, benzene and exposure group related metabolites, totaling 13 major categories

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Genetics , with some individuals being more genetically predisposed to addiction due to differences in how their brain responds to nicotine