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Initial item analysis Item discrimination was assessed via corrected item-total correlations

Smoking status of family members The smoking status of family members was assessed with the questions: Does your father smoke?, Does your mother smoke?, Do your siblings smoke? and Do your grandparents smoke?, with responses yes or no

Even secondhand smoke has been shown to affect inflammatory response and activate the NF-B pathway in mice sub-chronically exposed to this carcinogen [201, 202]

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