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In some countries, it is not uncommon to find the provision of highly developed access to healthcare and inclusive harm reduction and opioid substitution treatment for intravenous drug users, with a complete absence of concern or programmes addressing tobacco use

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In addition, these changes are often more prominent in adnexal structures than in interfollicular skin.[] In the present study, hyperkeratosis was seen in 86% cases of genital and 61% cases of EG ones