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When strict adherence to the FDA definition of a cigarette (which seems to require the presence of both nicotine and tobacco and to be dependent on high-temperature burning) is not intended, the committee uses the term cigarette-like. These products are basically paper-covered cylinders of approximately 90 mm length that, when lit, heated or burned (usually controlled in a very rigorous manner and at lower temperatures than conventional cigarettes), and puffed, allow smoke or vapors with what is recognized as the flavor of tobacco or cigarettes to be inhaled, leading to the absorption of nicotine into the body

Duke (18561925) was a tobacco manufacturer, industrialist, and philanthropist, of Durham, N.C., and New York City

The addictive nature of nicotine, coupled with the accessibility and social acceptance of cigarettes, contributes to the formidable challenge of quitting smoking [2]

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