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Of these 476 studies, 237 were included in the meta-analysis only, 211 were included in the narrative review only and 28 were included in both (Table 1)

In this article, inflammasome signaling is viewed as a promising but still incompletely understood mechanism in smoking-related OA, linking stress sensing, macrophage activation, cytokine maturation, and joint inflammation

Since the development of e-cigarettes, there has been an increase in the number of smokers who use and enquire about e-cigarettes when attempting to quit smoking [97, 98]

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