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Smokers thus develop age-related loss of brain volume that leads to an increased risk of dementia and is one of the ways how smoking harms the brain

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Although using a lower nicotine level e-liquid, especially under fixed voltage conditions, was related to lower nicotine exposure in comparison with higher nicotine e-liquid, the results of our daily aerosol exposure suggest that e-cigarettes were used more intensively with lower nicotine concentration e-liquids, supporting our previous findings 29,30

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