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To note, similar reductions in endothelial-dependent dilation have been identified after a single exposure to combustible tobacco products or e-cigarettes [115], although contradictory results are also available, supporting that acute exposure to neither combustible tobacco cigarettes nor ENDS had an effect on vascular function [87]

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Fun fact: if now many people still associate Marlboro with cowboys, bikes, auto racing, in general, with the world of stereotypical male values, in the 1920s Marlboro cigarettes were considered feminine

This varies by product, but the presence or absence of additives doesnt determine safety