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5 Ionocytes and PNECs, both expressing high levels of ion channels POU2F3 and FOXI1, were shown to be important for normal epithelial electrophysiology, as airliquid interface cultures deficient in both those proteins displayed hyperpolarization and lower conductance

Snorting any drug, including buprenorphine, has the potential to cause serious damage to the respiratory system that may lower the threshold of opioid abuse required to induce a fatal overdose

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