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E-cigarettes have experienced a significant gain in popularity as an alternative to traditional cigarette smoking, even among nonsmokers, and the industry has seen increasing sales

and Tobacco Nation: The inclusion of smoking, tobacco control policies and population characteristics for all 50 states allows for comparisons between individual states inside and outside of Tobacco Nation

However, these efforts were somewhat redundant, as candy cigarettes had already been made illegal in 2009 by the Tobacco Control Act, which banned candy and fruit-flavored cigarettes that appeal to children

As there are no previous studies that report the global prevalence of IBS using the Rome IV criteria, the high prevalence of IBS reported in our study is uncertain