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Heres a quick overview: Before drinking (prevention attempts): Eating a large meal beforehand Taking vitamins or supplements (e.g., B-complex, NAC, milk thistle) see vitamins for hangover prevention Drinking water in advance During drinking: Pacing drinks or alternating with water Choosing clear spirits over darker ones Avoiding certain beverages (like red wine or beer) After drinking (recovery attempts): Electrolytes or sports drinks Coffee or caffeine Greasy or heavy food Pain relievers (e.g., ibuprofen, acetaminophen) Hair of the dog (more alcohol) Sleep or napping Other approaches: Herbal remedies and tonics (including traditional options like Korean hangover drinks) Hydration powders and recovery mixes Sauna or sweating it out These approaches can make you feel slightly better in the moment, but they dont resolve the underlying stress your body is dealing with

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Food Chem Toxicol 118:198203 Kuklin V et al (2005) Tezosentan-induced attenuation of lung injury in endotoxemic sheep is associated with reduced activation of protein kinase C