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Most studies evaluated exposure to tobacco smoke quantitatively by reporting number of cigarettes per day, duration of smoking or age at starting to smoke, or in a cumulative way in terms of pack years 3 (number of packs of cigarettes smoked daily multiplied by the number of years of smoking)

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It is estimated that around 1 in 10 cigarette butts enter the aquatic environment after being transported from stormwater drains, and beaches to streams and waterways.After only an hour of contact with water, cigarette butts leach nicotine, lead, cadmium and heavy metals before becoming an ocean-contaminating microplastic waste that threatens the marine ecosystem

[Since nicotine is] similar in shape to the neurotransmitter acetylcholine, signaling increases in the brain, explains Lori A