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Through a combination of scRNA-seq and CRISPR knockout studies we unveiled a tuft-like cell population, and we provide strong evidence that disease-relevant rare cell types are connected by a branched lineage which proceeds from tuft-like cells to both ionocytes and PNECs

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In fact, not eating enough calcium puts you at risk for these stones because dietary calcium binds with dietary oxalates and phosphate in the gastrointestinal tract, so they can more easily leave the body

Season 1 follows two Louisiana detectives, Rust Cohle and Martin Hart, as they reopen a 1995 murder case of a sex worker with possible occult ties