strategies to avoid tobacco use The Bucket Approach – UW-CTRI – UW–Madison Alternative strategies for addressing tobacco

Abbreviations B[a]P benzo[ a ]pyrene DALYs disability-adjusted life years HDL high-density lipoprotein HONO nitrous acid LC-MS/MS liquid chromatographytandem mass spectrometry iso -NNAC 4-(methylnitrosamino)-4-(3-pyridyl)butyric acid iso -NNAL 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanol LDL low-density lipoprotein NNA 4-(methylnitrosamino)-4-(3-pyridyl)butanal NNK 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone NNN N -nitrosonornicotine NRU neutral red uptake PAHs polycyclic aromatic hydrocarbons PM particulate matter PM2.5 fine particulate matter ROS reactive oxygen species SHS secondhand smoke SIMH stress-induced mitochondrial hyperfusion THS thirdhand smoke TSNA tobacco-specific nitrosamine VOCs volatile organic compounds Biographies Peyton Jacob, III is a Research Chemist in the Division of Clinical Pharmacology at the University of California, San Francisco

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Ending combustible tobacco sales is essential to addressing health inequalities and promoting healthy human and economic development for future generations