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Durazzo, Over eight months of sustained abstinence from alcohol, active-smoking ALC (alcohol-dependent individuals) showed poorer recovery than never-smoking ALC on measures of learning, and both former-smoking ALC and active-smoking ALC recovered less than never-smoking ALC on processing speed measures. In other words: In alcoholics, nicotine interferes with their neurocognitive recovery during the first stages of their alcohol cessation. And yet the prevailing wisdom has long been that cigarette smoking should not be addressed in the early phases of treatment for fear that incorporating tobacco cessation into the treatment protocol might overwhelm individuals experiencing withdrawal symptoms from alcohol and drugs, according to the research in Substance Use and Misuse

Representing one objective approach for providing insight into the behavioral relevance of convergent gray matter decreases among smokers, we utilized emergent meta-analytic tools to delineate structurally impacted ROIs that tended to co-activate and their associated behavioral phenomena