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Here is a scathing ad from way back in 1965 just skewering Big Tobacco with a Us Cigarette Makers Would Rather Fight than Quit ad, mocking the old, long running Tareyton cigarette campaign of Id rather fight than switch. As a smoker smokes a dollar bill, the ad for Carry On reads: You think were going to let our billion-dollar industry go up in smoke

Adapted for the screen several times, most famously a 1952 film directed by Anthony Asquith and starring Michael Redgrave, Michael Denison, Edith Evans, Joan Greenwood, Dorothy Tutin, Margaret Rutherford, and Miles Malleson, and a 2002 film directed by Oliver Parker and starring Colin Firth, Rupert Everett, Frances O'Connor, Reese Witherspoon and Judi Dench

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This is a chronic inflammatory bowel disease which mainly affects the small intestine, however, it can involve any part of the gastrointestinal tract