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American journal of epidemiology, 179(7), 807823

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When data were below level of detection, the most conservative approach was adopted by taking the middle value of the range between the limit of quantification and detection for analysis (LD + (LQ-LD)/2)

"E-cigarettes are a consumer-driven revolution," Hon said, noting the array of products now on the market that address the needs of various groups, from people wanting to cut back or quit smoking to a new band of recreational "cloud-chasers" who use nicotine-free vapour to blow the biggest and densest clouds