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Using data from the largest study that looked at smoking and disease severity, which included 1,099 COVID-19 patients in China, scientists calculated that smokers were 1.4 times more likely to have severe symptoms of COVID-19 and approximately 2.4 times more likely to be admitted to an ICU, need mechanical ventilation, or die compared to non-smokers

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Other studies have found that smokers have smaller gray matter volumes (GMVs) in the thalamus, medial frontal cortex, cingulate cortex, and bilateral prefrontal cortex than non-smokers through voxel-based morphometry (VBM)

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