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so that the size of the article may be reduced in stowage, and the air expressed so as to render it less pregnable by outward accident, or exterior injury, than it would be in its natural condition

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Overall, the mitophagy-mediated upregulation of antiapoptotic proteins and downregulation of proapoptotic proteins leads to an increase in the antiapoptotic signal relative to the proapoptotic signal, which inhibits the release of cytochrome c, and prevents apoptosis by inactivating caspase-9/3