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It can also be caused by NSAIDs, acid reflux, smoking Pain is described as gnawing or burning and usually radiates to the back Patients typically present with epigastric pain that is worse with food (postprandial) It is most commonly found at the lesser curvature of the antrum PUD is the MC cause of non-hemorrhagic GI bleed , typically presenting as hematemesis (either red blood or coffee-ground emesis) or melena (black, tarry stool) Duodenal ulcers vs Gastric ulcers Upper endoscopy is the most accurate diagnostic test for peptic ulcer disease Biopsy for H

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