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At the same time, accumulated research on EndMT showed that endothelial dysfunction contributes to the pathogenesis of pulmonary hypertension [132] and pulmonary vascular endothelial cell apoptosis can promote the development of pulmonary hypertension, which is a common complication of COPD and is closely related to COPD progression [133]

Cytokine production also correlated with the number of years an individual smoked, for both current and past smokers

Also, protein levels of lung transferrin that binds extracellular iron (Fe3 +), were significantly decreased in the JUUL + HDM WT group compared to the WT air controls (Fig

Men 15.9.2