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The results of this study also showed that a higher level of nicotine dependence was associated with a higher risk for smoking relapse, and these results are consistent with the findings of a previous study of the users of the smoking cessation clinic of public health centers, which reported that a lower level of nicotine dependence was linked to a higher smoking cessation success rate [42]

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Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers: evidence for a dysfunctional nitric oxide synthase