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[Cubs president] Jed [Hoyer] says that a lot, too

Do not use if you continue to smoke, chew tobacco, use snuff, or use a nicotine gum or other nicotine containing products

Conversely, IQOS use was discouraged by concerns about unknown harms, due to the perceived lack of independent and longitudinal research, PMI disclaimers, written warnings on HEETS packaging, and the contents of HEETS [33]

The source of ROS varies between the gas or tar phase of cigarette smoke, monocytes, macrophages, neutrophils, and endogenous sources from xanthine oxidase, endothelial nitric oxide synthase (eNOS), and the mitochondrial electron transport chain ( 15 , 16 )