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A man is holding an iqos type e-cigarette from Philip Morris in a tobacco shop

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Some studies indicate obesity causes high serum uric acid.[ref] Other studies indicate that high uric acid levels cause an increase in obesity.[ref] In fact, some researchers theorize that humans found it advantageous to have higher uric acid levels because it promoted fat accumulation, which was helpful for survival throughout history.[ref] Interestingly, there seems to be a U-shaped curve for uric acid levels and BMI, with the lowest uric acid found in women with a BMI of 21.3 and men with a BMI of 19.1.[ref] While the complete picture isnt clear here, obesity combined with higher uric acid levels is also associated with a greater risk of high blood pressure than either condition separately.[ref] Heart problems: High uric acid levels are linked with a greater risk of heart problems and cardiovascular mortality

We aimed to assess the epidemiological features, natural course, and complications as well as compare them between smokers, alcoholics, and without tobacco or alcohol users