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Some studies have demonstrated that current smoking habits were associated with increased levels of GFR or creatinine clearance in the general population, 6, 10, 12, 14 whereas other studies have demonstrated decreased GFR levels in current smokers among the general population 7, 15 and diabetic patients

The evidence presented further shows that these factors play a key role in the development of a broad spectrum of smoking-related diseases, including CVDs, COPD, cancer, type 2 diabetes, Crohns disease, rheumatoid arthritis, psoriasis, PCOS, osteoporosis, MS and AD

The metal ion residues (Na + , K + , Ca 2+ , Mg 2+ ) introduced by catalysts could cause deposition and wear of engine components