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Pipe tobacco often costs less due to different tax rates

When absorbed through the skin via a patchor through the mouth and stomach when chewing nicotine gumnicotine is absorbed more slowly and therefore takes longer to reach the brain

Concerns on potential gateway effect E-cigarettes and vaporisers may cause non-smokers, particularly youths, to become addicted to nicotine, and serve as a gateway to experimentation and regular use of cigarettes later on

Experimental session procedures Each 58 h dosing session consisted of an acute drug administration period, lasting 8 h, followed by a two-night, three-day inpatient stay on a closed residential unit