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1 Introduction In recent years, nicotine salt technology has been widely used in new tobacco products, which form protonated nicotine using organic acidnicotine complexes, and nicotine exists mainly in the protonated form ( The production of satisfaction is mainly related to the effect of nicotine on the dopamine (DA) reward system in the brain, which produces euphoric and pleasurable sensory effects ( Compared with traditional methods, in recent years, in vivo fluorescence imaging methods for monitoring changes in DA release have been developed in the field of neuroscience ( in vivo ( In this study, we aimed to investigate the effects of exposure to various nicotine salts on the release of DA in the NAc, the reward center of the brain, using a photometric recording method to compare the pharmacological differences in the effects of different nicotine salts

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This absorption process is gradual compared to the rapid nicotine delivery from smoking, making it a safer alternative for managing cravings

van Dusseldorp and M