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Indeed, COPD stages 1 and 2 and the presence of emphysema were shown to be among the strongest independent risk factors for lung cancer, with respective hazard ratios of 1.4 and 3.5 in the Pittsburgh Lung Screening Study cohort [23, 60]

The analytic SAS and R code used in this study is available via GitHub at De-identified NHIS analytic datasets are accessible upon application through the NHIS Big Data Platform, subject to NHIS approval and data extraction procedures, and can be analyzed within NHIS-designated secure analysis environments

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