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What is nicotine dependence? Nicotine is the addictive ingredient in both vapes and cigarettes. When your body receives nicotine, receptors in the brain release a feel good chemical this is what makes Nicotine and Addiction StoryMD Compound Interest: The Chemicals in Cigarette Smoke & Their Effects New Poll Shows U.S. Adults Find Cigarettes Most Unsafe, Addictive Substance Southern Iowa Mental Health Center
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