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The proprietary expansion process used in manufacturing yields a greater volume of tobacco for the same low price and without compromising flavor, so you'll be pleasantly surprised when your bag is larger than expected

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INTRODUCTION Lifetime cigarette smoking has profound effects on health, affecting every organ in the body, and is causally associated with dozens of diseases and millions of deaths worldwide each year 1

This is followed by a condensation with glyceraldehyde-3-phosphate and a cyclization catalyzed by quinolinate synthase (QS) to give quinolinic acid