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Leia mais: The failed history of tobacco harm reduction The 2014 Surgeon Generals report on tobacco smoking confirmed cigarette engineering had caused an increase in lung adenocarcinomas since the 1960s, because of changes in cigarette design since the 1950s

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However, most reported studies were focused only on aldehyde per se , whereas exposure to the mixtures of aldehydes appears to be more common than that to a single aldehyde

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