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Were very excited about how much [our reduced-nicotine cigarettes] can help smokers to change their relationship with smoking for the better. Encouraging study results paired with the US FDAs impending plan to require all cigarettes sold in the US in the future to be minimally addictive or non-addictive, prompted 22nd Century to file a premarket tobacco product application (PMTA) with FDA to bring our reduced nicotine content cigarettes to market with MRTP [modified risk tobacco product] claims. The brand specifically created for that purpose was named VLN

2022 Dec 16;19(24):16931

Mother-to-child transmission of syphilis (congenital syphilis) is usually devastating to the fetus in cases where maternal infection is not detected and treated sufficiently early in pregnancy