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In recent years, it has been implied that TS may play a role in MS pathogenesis and that it might also affect how the disease progresses and how severe it will be (Ghasemi et al., 2017)

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We separately analyzed theoretical changes in program spending for one biosimilar product (ZIEXTENZO, Q5120) that has reported negative ASP data for all NDCs for three consecutive quarters beginning with the second calendar quarter of 2022, and calculated the payment limit under our proposed method for biosimilars with negative or zero ASP data and changes in program spending for the three impacted quarters had our proposed payment approach been applied

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