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Shiels, M

Discussion: Given their different pharmacological profiles, comparison between WAY-100,635 and S-15535 indicates that postsynaptic 5-HT 1A receptors mediate the behavioral effects of prior nicotine and fluoxetine exposure

Second, product use was limited to a single time-controlled use of an NP product on a single day, and as such we cannot infer whether nicotine pharmacokinetics will change over time following continued use or when individuals use NPs for shorter or longer time periods than the 60-min use period stipulated in this study protocol

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